{"id":8810122,"date":"2026-09-09T15:00:11","date_gmt":"2026-09-09T15:00:11","guid":{"rendered":"https:\/\/www.costamedicalservices.com\/?page_id=8810122"},"modified":"2026-09-10T08:01:03","modified_gmt":"2026-09-10T08:01:03","slug":"wegovy-or-mounjaro-the-differences-and-how-treatment-is-chosen","status":"publish","type":"page","link":"https:\/\/www.costamedicalservices.com\/sv\/portugal\/medical-library\/wegovy-or-mounjaro-the-differences-and-how-treatment-is-chosen\/","title":{"rendered":"Wegovy or Mounjaro: the differences and how treatment is chosen"},"content":{"rendered":"<style>.entry-title{display:none!important}.cmsarticle{--ink:#103d56;--muted:#647d8b;--blue:#2d78da;--cyan:#1baec5;--green:#16856f;--line:#d9e7ed;--soft:#f3f8fa;--warn:#fff7e8;--rose:#fff3f3;--shadow:0 18px 44px rgba(16,61,86,.11)}\n.cmsarticle,.cmsarticle *{box-sizing:border-box}.cmsarticle 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a{border-radius:13px;background:var(--soft);padding:14px;text-decoration:none;font-size:13px;font-weight:800}.cmsarticle .related a span{display:block;font-size:11px;color:var(--muted);font-weight:600;margin-top:3px}.cmsarticle .reviewer{display:grid;grid-template-columns:70px 1fr;gap:17px;padding:22px;border:1px solid var(--line);border-radius:18px;margin:30px 0 22px;background:#fff}.cmsarticle .avatar{width:70px;height:70px;border-radius:50%;display:grid;place-items:center;background:linear-gradient(145deg,#daf4f7,#e8eefb);font-size:22px;font-weight:900}.cmsarticle .reviewer h3{margin:0 0 3px}.cmsarticle .reviewer p{font-size:14px;color:var(--muted);margin:0}.cmsarticle .seal{display:inline-block;margin-top:8px;color:var(--green);font-size:12px;font-weight:850}.cmsarticle .sources{font-size:14px;color:var(--muted);border-top:1px solid var(--line);padding-top:24px}.cmsarticle .sources h2{font-size:25px;margin-top:0}.cmsarticle .sources li{margin-bottom:9px}.cmsarticle .cta{margin-top:34px;padding:27px;border-radius:20px;background:var(--ink);color:#fff}.cmsarticle .cta h2{color:#fff;margin:0 0 7px}.cmsarticle .cta p{color:#c7d9e2}.cmsarticle .cta a{display:inline-block;padding:13px 18px;border-radius:12px;background:var(--blue);color:#fff;text-decoration:none;font-weight:850}.cmsarticle .disclaimer{margin-top:20px;padding:19px 21px;border:1px solid #cfdde4;border-radius:16px;background:#f7fafb;color:var(--muted);font-size:12px;line-height:1.6}.cmsarticle .disclaimer strong{display:block;color:var(--ink);font-size:13px;margin-bottom:5px}.cmsarticle .disclaimer p{margin:0}\n@media(max-width:850px){.cmsarticle .layout{grid-template-columns:1fr}.cmsarticle .toc{position:relative;top:auto}.cmsarticle .cards{grid-template-columns:1fr 1fr}.cmsarticle .related-grid{grid-template-columns:1fr}}\n@media(max-width:560px){.cmsarticle .page{padding:13px 15px 60px}.cmsarticle .hero{min-height:690px;padding:27px 21px;background-image:linear-gradient(0deg,rgba(255,255,255,.99) 0%,rgba(255,255,255,.95) 51%,rgba(255,255,255,.06) 75%),var(--hero);background-position:68% center}.cmsarticle .hero h1{font-size:40px}.cmsarticle .dek{font-size:17px}.cmsarticle .layout{gap:26px}.cmsarticle .summary{padding:22px 20px}.cmsarticle article{font-size:16px}.cmsarticle article h2{font-size:28px}.cmsarticle .cards,.cmsarticle .checklist{grid-template-columns:1fr}.cmsarticle .reviewer{grid-template-columns:56px 1fr}.cmsarticle .avatar{width:56px;height:56px;font-size:18px}}\n<\/style>\n<div class=\"cmsarticle\" lang=\"en-GB\">\n<div class=\"page\"><a class=\"back\" href=\"https:\/\/www.costamedicalservices.com\/portugal\/medical-library\/\">\u2190 Return to the Medical Library<\/a><\/p>\n<header class=\"hero\" style=\"--hero:url('https:\/\/www.costamedicalservices.com\/wp-content\/uploads\/2026\/03\/pen.png')\">\n<div class=\"hero-copy\">\n<div class=\"eyebrow\">Comparisons \u00b7 medical guide<\/div>\n<h1>Wegovy or Mounjaro: the differences and how treatment is chosen<\/h1>\n<p class=\"dek\">Medical comparison between Wegovy and Mounjaro: active ingredients, indication, results, tolerance and choice.<\/p>\n<div class=\"tags\"><span>Wegovy vs Mounjaro<\/span><span>semaglutide<\/span><span>tirzepatide<\/span><span>comparative<\/span><\/div>\n<div class=\"byline\"><span><strong>Reading:<\/strong> 13 minutes<\/span><span><strong>Updated:<\/strong> August 30, 2026<\/span><span><strong>Medical review:<\/strong> Dr Paulo<\/span><\/div>\n<\/div>\n<\/header>\n<div class=\"layout\">\n<nav class=\"toc\" aria-label=\"Content\"><b>In this article<\/b><a href=\"#resumen\">Summary and conclusions<\/a><a href=\"#s1\">Basic differences<\/a><a href=\"#s2\">What the studies say<\/a><a href=\"#s3\">How to decide in consultation<\/a><a href=\"#s4\">Useful questions before choosing<\/a><a href=\"#fuentes\">Official sources<\/a><\/nav>\n<article>\n<section class=\"summary\" id=\"resumen\">\n<div class=\"summary-label\">Summary and conclusions<\/div>\n<h2>The essentials in less than a minute<\/h2>\n<ul>\n<li>Wegovy contains semaglutide and acts on GLP-1; Mounjaro contains tirzepatide and acts on GIP and GLP-1.<\/li>\n<li>Clinical trial averages do not predict individual outcome nor are they a substitute for a direct comparison.<\/li>\n<li>The choice depends on indication, history, tolerance, concomitant medication, availability and follow-up.<\/li>\n<li>\u201cMore powerful\u201d does not automatically mean \u201cbetter for me.\u201d<\/li>\n<\/ul>\n<\/section>\n<section id=\"s1\">\n<h2>Basic differences<\/h2>\n<div class=\"table-wrap\">\n<table>\n<caption>Wegovy and Mounjaro at a glance<\/caption>\n<thead>\n<tr>\n<th>Appearance<\/th>\n<th>wegovy<\/th>\n<th>Mounjaro<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Active ingredient<\/td>\n<td>Semaglutide<\/td>\n<td>Tirzepatide<\/td>\n<\/tr>\n<tr>\n<td>Receivers<\/td>\n<td>GLP-1<\/td>\n<td>GIP and GLP-1<\/td>\n<\/tr>\n<tr>\n<td>Injectable regimen<\/td>\n<td>Weekly, with climbing<\/td>\n<td>Weekly, with climbing<\/td>\n<\/tr>\n<tr>\n<td>prescription<\/td>\n<td>Yes<\/td>\n<td>Yes<\/td>\n<\/tr>\n<tr>\n<td>Election<\/td>\n<td colspan=\"2\">Individual clinical assessment and follow-up.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>Both are authorised as a complement to a diet with fewer calories and greater physical activity in people who meet the criteria. They are not cosmetic products or comparable purchases based on price alone.<\/p>\n<\/section>\n<section id=\"s2\">\n<h2>What the studies say<\/h2>\n<p>The fundamental studies showed relevant average weight losses, but they were carried out in specific populations, doses and durations. Directly comparing a STEP 1 percentage to a SURMOUNT-1 percentage is illustrative, not proof of individual superiority.<\/p>\n<div class=\"answer\"><strong>Correct reading of an average<\/strong>An average result groups major, minor responses and dropouts. It does not guarantee how much a person will lose or what treatment they will tolerate best.<\/div>\n<p>Also important for an informed comparison are the proportion of people who discontinued, adverse effects, study conditions, and the lifestyle intervention that accompanied the medication.<\/p>\n<\/section>\n<section id=\"s3\">\n<h2>How to decide in consultation<\/h2>\n<div class=\"cards\">\n<div class=\"mini\"><b>1<\/b><strong>Indication<\/strong><span>BMI, comorbidities and clinical objective.<\/span><\/div>\n<div class=\"mini\"><b>2<\/b><strong>Safety<\/strong><span>History, medication and risks.<\/span><\/div>\n<div class=\"mini\"><b>3<\/b><strong>Sustainability<\/strong><span>Tolerance, monitoring and continuity.<\/span><\/div>\n<\/div>\n<p>Diabetes, treatments that can cause hypoglycemia, digestive symptoms, diabetic eye disease, pregnancy or pregnancy planning, and ability to maintain follow-up are also reviewed.<\/p>\n<\/section>\n<section id=\"s4\">\n<h2>Useful questions before choosing<\/h2>\n<ul>\n<li>Do I comply with the authorised indication?<\/li>\n<li>What history or medications change the risk?<\/li>\n<li>What would we do if I cannot tolerate the dose increase?<\/li>\n<li>How will we measure benefit beyond weight?<\/li>\n<li>What plan exists for nutrition, physical activity and maintenance?<\/li>\n<\/ul>\n<p>The best option is the one that can be used in an indicated, safe and sustainable way, not necessarily the one that tops a table of averages.<\/p>\n<\/section>\n<section class=\"related\">\n<h2>Continue on the right route<\/h2>\n<p>Related medical guides and service pages. This article provides general information; treatment and prescribing decisions require an individual medical assessment.<\/p>\n<div class=\"related-grid\"><a href=\"https:\/\/www.costamedicalservices.com\/portugal\/medical-library\/wegovy-or-mounjaro-the-differences-and-how-treatment-is-chosen\/\">GLP-1 comparison<span>Clinical information and consultation<\/span><\/a><a href=\"https:\/\/www.costamedicalservices.com\/portugal\/weight-loss-injections\/\">GLP-1<span>Clinical information and consultation<\/span><\/a><a href=\"https:\/\/www.costamedicalservices.com\/portugal\/telehealth\/online-doctor\/\">Online medical consultation<span>Clinical information and consultation<\/span><\/a><\/div>\n<\/section>\n<section class=\"reviewer\">\n<div class=\"avatar\">P.B.<\/div>\n<div>\n<h3>Medically reviewed by Dr Paulo<\/h3>\n<p>Medical reviewer for Costa Medical Services. Clinical coherence, safety and source quality reviewed.<\/p>\n<p><span class=\"seal\">\u2713 Ordem dos M\u00e9dicos Portugal 69376 \u00b7 Review August 30, 2026<\/span><\/div>\n<\/section>\n<section class=\"sources\" id=\"fuentes\">\n<h2>Official and clinical sources<\/h2>\n<ol>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/wegovy\">EMA: Wegovy EPAR<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/mounjaro\">EMA: Mounjaro EPAR<\/a><\/li>\n<\/ol>\n<p>Regulatory information may change. Before publishing in WordPress, you should double-check the current version of the SmPC and leaflet.<\/p>\n<\/section>\n<section class=\"cta\">\n<h2>Do you need a medical evaluation?<\/h2>\n<p>The consultation is used to review symptoms, history, medication and decide if online management is appropriate or if you need in-person care.<\/p>\n<p><a href=\"https:\/\/www.costamedicalservices.com\/portugal\/telehealth\/online-doctor\/\">See medical consultation<\/a><\/section>\n<aside class=\"disclaimer portugal-note\"><strong>Information for patients in Portugal<\/strong><\/p>\n<p>Medicine availability, approved indications and dispensing requirements may differ by country. For Portugal, current regulatory information should be checked with <a href=\"https:\/\/www.infarmed.pt\/\">INFARMED<\/a>, and treatment must be assessed individually.<\/p>\n<\/aside>\n<aside class=\"disclaimer\"><strong>Notice about AI and medical information<\/strong><\/p>\n<p>This article has been prepared with the help of artificial intelligence tools and may contain errors, inaccuracies or omissions. It is provided for general guidance only and is never a substitute for medical advice, examination, diagnosis or the instructions in the package leaflet. Do not start, stop, or modify a medication or delay urgent care based on this content alone.<\/p>\n<\/aside>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<p><script type=\"application\/ld+json\" id=\"cms-confirmed-medical-review\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"MedicalWebPage\",\"@id\":\"https:\/\/www.costamedicalservices.com\/portugal\/medical-library\/wegovy-or-mounjaro-the-differences-and-how-treatment-is-chosen\/\",\"url\":\"https:\/\/www.costamedicalservices.com\/portugal\/medical-library\/wegovy-or-mounjaro-the-differences-and-how-treatment-is-chosen\/\",\"inLanguage\":\"en-GB\",\"reviewedBy\":{\"@type\":\"Physician\",\"name\":\"Dr Paulo\",\"identifier\":\"Ordem dos M\u00e9dicos Portugal 69376\"},\"lastReviewed\":\"2026-08-30\",\"name\":\"Wegovy or Mounjaro: the differences and how treatment is chosen\",\"description\":\"Medical comparison between Wegovy and Mounjaro: active ingredients, indication, results, tolerance and choice.\",\"mainEntityOfPage\":\"https:\/\/www.costamedicalservices.com\/portugal\/medical-library\/wegovy-or-mounjaro-the-differences-and-how-treatment-is-chosen\/\",\"dateModified\":\"2026-09-09\",\"author\":{\"@type\":\"MedicalOrganization\",\"name\":\"Costa Medical Services\"},\"publisher\":{\"@type\":\"MedicalOrganization\",\"name\":\"Costa Medical Services\"},\"isPartOf\":{\"@type\":\"CollectionPage\",\"url\":\"https:\/\/www.costamedicalservices.com\/portugal\/medical-library\/\",\"name\":\"Medical Library for Patients in Portugal\"},\"spatialCoverage\":{\"@type\":\"Country\",\"name\":\"Portugal\"},\"keywords\":\"Wegovy vs Mounjaro, semaglutide, tirzepatide, comparative\"}<\/script><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2190 Return to the Medical Library Comparisons \u00b7 medical guide Wegovy or Mounjaro: the differences and how treatment is chosen Medical comparison between Wegovy and Mounjaro: active ingredients, indication, results, tolerance and choice. Wegovy vs Mounjarosemaglutidetirzepatidecomparative Reading: 13 minutesUpdated: August 30, 2026Medical review: Dr Paulo In this articleSummary and conclusionsBasic differencesWhat the studies sayHow to [&hellip;]<\/p>\n","protected":false},"author":10,"featured_media":0,"parent":8810000,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"class_list":["post-8810122","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Wegovy or Mounjaro: the differences and how treatment is chosen - English Speaking Doctor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.costamedicalservices.com\/portugal\/medical-library\/wegovy-or-mounjaro-the-differences-and-how-treatment-is-chosen\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Wegovy or Mounjaro: the differences and how treatment is chosen - English Speaking Doctor\" \/>\n<meta property=\"og:description\" content=\"\u2190 Return to the Medical Library Comparisons \u00b7 medical guide Wegovy or Mounjaro: the differences and how treatment is chosen Medical comparison between Wegovy and Mounjaro: active ingredients, indication, results, tolerance and choice. 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