STIs and STDs
bacterial STI

Syphilis: symptoms, testing and treatment

Syphilis can go through different phases. It may begin with a painless ulcer and later cause a rash, glands, or general symptoms; You may also remain symptom-free.

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Possible symptoms

Painless genital, anal or oral ulcer

This symptom can also have other causes; It does not by itself confirm an STI.

Rash, including on palms or soles

This symptom can also have other causes; It does not by itself confirm an STI.

Lymph nodes, fever, or complete absence of symptoms

This symptom can also have other causes; It does not by itself confirm an STI.

Tests and diagnosis

Diagnosis requires tests, usually blood tests and, in specific situations, a sample of the lesion. The date of exposure and previous treatments help interpret the result.

Date and type of contact
Symptoms and exposed areas
Previous tests and treatments
Other STIs that should be ruled out

Treatment and follow-up

Syphilis is cured with appropriate antibiotics, but the regimen and follow-up depend on the phase, pregnancy, and possible neurological involvement. Couples should receive counseling and testing.

When to seek prompt care

Request urgent attention for neurological or visual alterations, pregnancy with suspected syphilis, sudden hearing loss or poor general condition.

Other STI guides

Information based on resources from the WHO and the Ministry of Health. This page guides, not diagnoses.